How to enhance SIRT1 for healthy and active aging

Aging is a complex biological process that affects all multicellular organisms, characterized by a progressive decline in cellular function and increased vulnerability to diseases. This phenomenon manifests through physiological changes impacting overall health, such as DNA damage accumulation, increased oxidative stress, and chronic inflammation, among others. These factors are closely linked to the development of […]
Beyond antioxidants

Understanding oxidative stress Oxidative stress is a condition that arises when there is an imbalance between the production of reactive oxygen species (ROS) and the body’s ability to neutralize these harmful molecules. ROS are highly reactive molecules that can damage various cellular components, including lipids, proteins, and DNA. This damage can lead to a range […]
Resveratrol or Pterostilbene? A review of two promising stilbenes

Stilbenes are phytochemicals, a subclass of polyphenolic compounds. They are naturally found in a wide variety of plant based dietary sources such as grapes, blueberries, red wine, and some other plants. Among the well-known stilbenes are resveratrol, which is the first discovered and likely the most famous, and pterostilbene, which was discovered later and shows […]
Radiation Impact on Health and Prevention of its Effects

What is ionizing radiation? Radiation can be classified according to its effect on matter. Normally, “radiation” refers to ionizing radiation[1], meaning the separation of electrons from its atoms, such as cosmic rays, X-rays, as well as the radiation emitted by radioactive materials, which can cause detrimental health effects. Whether undergoing diagnostic imaging (e.g., a CT […]
How can we overcome the stability issue in Dietary Supplements?

Stability Issues in Dietary Supplements Most nutraceutical ingredients show degradation. Dietary supplements usually contain a mixture of ingredients, mostly natural products and plant extracts. Ingredients used to be of natural origin, but sometimes a synthetic product (identical to the natural one) is used due to some technical, cost or availability reasons. In any case, all of […]
How can we improve the stability of CoQ10?

What is coenzyme Q10? CoQ10 stands for Coenzyme Q10. It can be found in animals as an endogenous substance, in other words, we have it in our body to support relevant physiological functions. But its level decreases with age, which is believed to impact health and well-being. Also, when taking statins (drugs used to decrease […]
Stability Issues in Dietary Supplements: Vitamin D3

A case study What is Vitamin D3? Vitamin D is a fat-soluble prohormone that stimulates calcium absorption in the gut and maintains adequate serum calcium and phosphate concentration. Vitamin D2 and vitamin D3 are the main forms of Vitamin D used by humans. Vitamin D3 is produced naturally by the body when skin is exposed to ultraviolet radiation […]
Improving the bioavailability of pterostilbene

Nutraceutical ingredients are natural compounds, usually extracted and purified from both food and nonfood plants.1 In recent years, nutraceuticals have been experienced an increased interest because their presumed safety and potential therapeutic effects allow health claims as food supplements with a variety of health benefits for humans and animals.2 Among the plethora of known nutraceutical […]
Crystal Engineering

Bienestar A new vitamin D ‘made in Spain’ arrives with more advantages. CIRCE Scientific, a ‘startup’ created by two friends (from the universities of the Balearic Islands and Barcelona), has developed a crystalline form of this molecule that makes it much more heat stable and prevents dosing errors. Foto: Unsplash. By Patricia Matey 30/07/2021 – […]
Dietary Supplements during COVID-19

There is no food or dietary supplement that enhances or strengthens the immune system in a healthy population without nutritional deficiencies. Although some vitamins (A, B6, B12, C, D) or minerals (zinc, selenium, copper, magnesium) have shown to play a role in the immune response to infections, none of them have shown to consistently prevent […]