Cocrystals are a combination of two components, an active ingredient and a coformer, which interact on a molecular level and crystallize in the same crystal lattice. This unique combination shows improved physicochemical properties compared with the free active ingredient crystal.
Poor aqueous solubility and low oral bioavailability are the major constraints to unlock the full health benefits of active ingredients.
CIRCE has discovered new solid forms (cocrystals) of selected ingredients for the healthy living and longevity that present huge improvements compared with the original ones in regards to solubility, stability, and bioavailability, unlocking their health benefits and market potential.
Improved products (better stability, solubility, bioavailability)
Can be formulated for further improvement
New product patents (Extended protection)
Viable solid form allows product diversification
CIRCE has developed an advanced technological platform to identify new crystalline solid forms for synergistic active ingredients and polyphenols with improved properties to maximize the guarantee of success while reducing costs.